The goal of the Framingham Heart Study cell line project was to create a renewable resource of DNA to meet the distribution demands of approved genetic research projects.
Background: Starting in 1997, consenting participants had blood collected for the explicit purpose of creating lymphoblast cell lines from which DNA can be isolated.
Current Policy: Requests for DNA samples from any Framingham participant are reviewed by the DNA Committee, including DNA samples from those that have viable lymphoblast cell lines and from those who do not have cell lines.
Unfortunately, there are participants who do not have viable cell lines. Many of these participants have consented to genetic research using their genetic material. DNA exists on these participants from whole blood isolation, but it is non-renewable and considered precious. There are varying amounts of DNA available for these individuals, from 0.1 – 4000 ug. For access to these DNA samples, additional review by the Framingham Genetic Steering Committee (FGSC) and Framingham Executive Committee is required.
General Guidelines for Precious DNA samples:
Questions should be directed to Heather Arruda at firstname.lastname@example.org
Last Updated: Legacy Policy