The Framingham Heart Study is a project of Boston University & the National Heart, Lung, & Blood Institute.
The Framingham Heart Study is a project of Boston University & the National Heart, Lung, & Blood Institute.

Framingham Heart Study Bibliography – 2008

Ackert-Bicknell CL, Demissie S, Marin de EC, Hsu YH, DeMambro VE, Karasik D, Cupples LA, Ordovas JM, Tucker KL, Cho K, Canalis E, Paigen B, Churchill GA, Forejt J, Beamer WG, Ferrari S, Bouxsein ML, Kiel DP, Rosen CJ: PPARG by dietary fat interaction influences bone mass in mice and humans. J Bone Miner Res 2008;23:1398-1408 (PubMed ID Number: 18707223 PMCID: PMC2683155).

Adams RJ, Albers G, Alberts MJ, Benavente O, Furie K, Goldstein LB, Gorelick P, Halperin J, Harbaugh R, Johnston SC, Katzan I, Kelly-Hayes M, Kenton EJ, Marks M, Sacco RL, Schwamm LH, American Heart Association, American Stroke Association: Update to the AHA/ASA recommendations for the prevention of stroke in patients with stroke and transient ischemic attack. Stroke 2008;39:1647-1652 (PubMed ID Number: 18322260).

Ankle Brachial Index Collaboration, Fowkes FG, Murray GD, Butcher I, Heald CL, Lee RJ, Chambless LE, Folsom AR, Hirsch AT, Dramaix M, deBacker G, Wautrecht JC, Kornitzer M, Newman AB, Cushman M, Sutton-Tyrrell K, Fowkes FG, Lee AJ, Price JF, D’Agostino RB, Murabito JM, Norman PE, Jamrozik K, Curb JD, Masaki KH, Rodriguez BL, Dekker JM, Bouter LM, Heine RJ, Nijpels G, Stehouwer CD, Ferrucci L, McDermott MM, Stoffers HE, Hooi JD, Knottnerus JA, Ogren M, Hedblad B, Witteman JC, Breteler MM, Hunink MG, Hofman A, Criqui MH, Langer RD, Fronek A, Hiatt WR, Hamman R, Resnick HE, Guralnik J, McDermott MM: Ankle brachial index combined with Framingham Risk Score to predict cardiovascular events and mortality: a meta-analysis. JAMA 2008;300:197-208 (PubMed ID Number: 18612117 PMCID: PMC2932628).

Bureau A, Diallo MS, Ordovas JM, Cupples LA: Estimating interaction between genetic and environmental risk factors: efficiency of sampling designs within a cohort. Epidemiology 2008;19:83-93 (PubMed ID Number: 18091418).

Chami HA, Devereux RB, Gottdiener JS, Mehra R, Roman MJ, Benjamin EJ, Gottlieb DJ: Left ventricular morphology and systolic function in sleep-disordered breathing: the sleep heart health study. Circulation 2008;117:2599-2607 (PubMed ID Number: 18458174 PMCID: PMC2813728).

Cho K, Demissie S, Dupuis J, Cupples LA, Kathiresan S, Beck TJ, Karasik D, Kiel DP: Polymorphisms in the endothelial nitric oxide synthase gene and bone density/ultrasound and geometry in humans. Bone 2008;42:53-60 (PubMed ID Number: 17980690 PMCID: PMC2386517).

Christakis NA, Fowler JH: The collective dynamics of smoking in a large social network. N Engl J Med 2008;358:2249-2258 (PubMed ID Number: 18499567 PMCID: PMC2822344).

Cupples LA: Family study designs in the age of genome-wide association studies: experience from the Framingham Heart Study. Curr Opin Lipidol 2008;19:144-150 (PubMed ID Number: 18388694).

D’Agostino RB, Sr., Vasan RS, Pencina MJ, Wolf PA, Cobain M, Massaro JM, Kannel WB: General cardiovascular risk profile for use in primary care: the Framingham Heart Study. Circulation 2008;117:743-753 (PubMed ID Number: 18212285).

Das RR, Seshadri S, Beiser AS, Kelly-Hayes M, Au R, Himali JJ, Kase CS, Benjamin EJ, Polak JF, O’Donnell CJ, Yoshita M, D’Agostino RB, Sr., DeCarli C, Wolf PA: Prevalence and correlates of silent cerebral infarcts in the Framingham offspring study. Stroke 2008;39:2929-2935 (PubMed ID Number: 18583555 PMCID: PMC2712254).

Dehghan A, Kottgen A, Yang Q, Hwang SJ, Kao WL, Rivadeneira F, Boerwinkle E, Levy D, Hofman A, Astor BC, Benjamin EJ, van Duijn CM, Witteman JC, Coresh J, Fox CS: Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study. Lancet 2008;372:1953-1961 (PubMed ID Number: 18834626 PMCID: PMC2803340).

Fayman M, Niu J, Zhang YQ, Felson DT, Sack B, Aliabadi P, Selhub J, Hunter DJ: The relation of plasma homocysteine to radiographic knee osteoarthritis. Osteoarthritis Cartilage 2008; (PubMed ID Number: 19073367 PMCID: PMC2758241).

Foster MC, Hwang SJ, Larson MG, Lichtman JH, Parikh NI, Vasan RS, Levy D, Fox CS: Overweight, obesity, and the development of stage 3 CKD: the Framingham Heart Study. Am J Kidney Dis 2008;52:39-48 (PubMed ID Number: 18440684 PMCID: PMC2531220).

Foster MC, Keyes MJ, Larson MG, Vita JA, Mitchell GF, Meigs JB, Vasan RS, Benjamin EJ, Fox CS: Relations of measures of endothelial function and kidney disease: The Framingham Heart Study. Am J Kidney Dis. 2008 Nov;52(5):859-67. Epub 2008 Jul 9. (PubMed ID Number: 18617305 PMCID: PMC2665728).

Fowler JH, Christakis NA: Dynamic spread of happiness in a large social network: longitudinal analysis over 20 years in the Framingham Heart Study. BMJ 2008;337:a2338 (PubMed ID Number: 19056788 PMCID: PMC2600606).

Fox CS, Pencina MJ, D’Agostino RB, Murabito JM, Seely EW, Pearce EN, Vasan RS: Relations of thyroid function to body weight: cross-sectional and longitudinal observations in a community-based sample. Arch Intern Med 2008;168:587-592 (PubMed ID Number: 18362250).

Fox CS, Pencina MJ, Wilson PW, Paynter NP, Vasan RS, D’Agostino RB, Sr.: Lifetime risk of cardiovascular disease among individuals with and without diabetes stratified by obesity status in the Framingham heart study. Diabetes Care 2008;31:1582-1584 (PubMed ID Number: 18458146 PMCID: PMC2494632).

Frankel DS, Meigs JB, Massaro JM, Wilson PW, O’Donnell CJ, D’Agostino RB, Tofler GH: Von Willebrand factor, type 2 diabetes mellitus, and risk of cardiovascular disease: the Framingham offspring study. Circulation 2008;118:2533-2539 (PubMed ID Number: 19029465 PMCID:PMC2746947).

Freiberg MS, Pencina MJ, D’Agostino RB, Lanier K, Wilson PW, Vasan RS: BMI vs. waist circumference for identifying vascular risk. Obesity (Silver Spring) 2008;16:463-469 (PubMed ID Number: 18239660).

Goessling W, Massaro JM, Vasan RS, D’Agostino RB, Sr., Ellison RC, Fox CS: Aminotransferase levels and 20-year risk of metabolic syndrome, diabetes, and cardiovascular disease. Gastroenterology 2008;135:1935-44, 1944 (PubMed ID Number: 19010326).

Govindaraju DR, Adrienne CL, Kannel WB, O’Donnell CJ, Atwood LD, D’Agostino RB, Sr., Fox CS, Larson M, Levy D, Murabito J, Vasan RS, Lee SG, Wolf PA, Benjamin EJ: Chapter 2 genetics of the Framingham Heart Study population. Adv Genet 2008;62:33-65 (PubMed ID Number: 19010253 PMCID: PMC3014216).

Guo CY, Lunetta KL, Destefano AL, Cupples LA. Combined haplotype relative risk (CHRR): a general and simple genetic association test that combines trios and unrelated case-controls. Genet Epidemiol. 2008 Jul 17;33(1):54-62. [Epub ahead of print] (PubMed ID Number: 18636528 PMCID: PMC2700841).

Guo CY, Cupples LA, Yang Q: Testing informative missingness in genetic studies using case-parent triads. Eur J Hum Genet 2008;16:992-1001 (PubMed ID Number: 18337731).

Hamburg NM, Keyes MJ, Larson MG, Vasan RS, Schnabel R, Pryde MM, Mitchell GF, Sheffy J, Vita JA, Benjamin EJ: Cross-sectional relations of digital vascular function to cardiovascular risk factors in the Framingham Heart Study. Circulation 2008;117:2467-2474 (PubMed ID Number: 18458169 PMCID: PMC2734141).

Hamburg NM, Larson MG, Vita JA, Vasan RS, Keyes MJ, Widlansky ME, Fox CS, Mitchell GF, Levy D, Meigs JB, Benjamin EJ: Metabolic syndrome, insulin resistance, and brachial artery vasodilator function in Framingham Offspring participants without clinical evidence of cardiovascular disease. Am J Cardiol 2008;101:82-88 (PubMed ID Number: 18157970 PMCID: PMC2214853).

Harvey WF, Niu J, Zhang Y, McCree PI, Felson DT, Nevitt M, Xu L, Aliabadi P, Hunter DJ: Knee alignment differences between Chinese and Caucasian subjects without osteoarthritis. Ann Rheum Dis 2008;67:1524-1528 (PubMed ID Number: 18230630).

Hernandez-Molina G, Neogi T, Hunter DJ, Niu J, Guermazi A, Reichenbach S, Roemer FW, McLennan CE, Felson DT: The association of bone attrition with knee pain and other MRI features of osteoarthritis. Ann Rheum Dis 2008;67:43-47 (PubMed ID Number: 19623678).

Hivert MF, Manning AK, McAteer JB, Florez JC, Dupuis J, Fox CS, O’Donnell CJ, Cupples LA, Meigs JB. Common variants in the adiponectin gene (ADIPOQ) associated with plasmaadiponectin levels, type 2 diabetes, and diabetes-related quantitative traits: the Framingham Offspring Study. Diabetes. 2008 Dec;57(12):3353-9. Epub 2008 Sep 5 (PubMed ID Number: 18776141 PMCID: PMC2584143).

Hivert MF, Sullivan LM, Fox CS, Nathan DM, D’Agostino RB, Sr., Wilson PW, Meigs JB: Associations of adiponectin, resistin, and tumor necrosis factor-alpha with insulin resistance. J Clin Endocrinol Metab 2008;93:3165-3172 (PubMed ID Number: 18492747 PMCID: PMC2515087).

Hoffmann U, Massaro JM, Fox CS, Manders E, O’Donnell CJ: Defining normal distributions of coronary artery calcium in women and men (from the Framingham Heart Study). Am J Cardiol 2008;102:1136-41, 1141 (PubMed ID Number: 18940279).

Hunter DJ, Niu JB, Zhang Y, Lavalley M, McLennan CE, Hudelmaier M, Eckstein F, Felson DT: Premorbid knee osteoarthritis is not characterised by diffuse thinness: the Framingham Osteoarthritis Study. Ann Rheum Dis 2008;67:1545-1549 (PubMed ID Number: 18218668).

Ingelsson E, Gona P, Larson MG, Lloyd-Jones DM, Kannel WB, Vasan RS, Levy D: Altered blood pressure progression in the community and its relation to clinical events. Arch Intern Med 2008;168:1450-1457 (PubMed ID Number: 18625926).

Ingelsson E, Larson MG, Yin X, Wang TJ, Meigs JB, Lipinska I, Benjamin EJ, Keaney JF, Jr., Vasan RS: Circulating ghrelin, leptin, and soluble leptin receptor concentrations and cardiometabolic risk factors in a community-based sample. J Clin Endocrinol Metab 2008;93:3149-3157 (PubMed ID Number: 18492761 PMCID: PMC2515078).

Ingelsson E, Pencina MJ, Levy D, Aragam J, Mitchell GF, Benjamin EJ, Vasan RS: Aortic root diameter and longitudinal blood pressure tracking. Hypertension 2008;52:473-477 (PubMed ID Number: 18663156 PMCID: PMC2856950).

Ji W, Foo JN, O’Roak BJ, Zhao H, Larson MG, Simon DB, Newton-Cheh C, State MW, Levy D, Lifton RP: Rare independent mutations in renal salt handling genes contribute to blood pressure variation. Nat Genet 2008;40:592-599 (PubMed ID Number: 18391953).

Johnson AD, Handsaker RE, Pulit SL, Nizzari MM, O’Donnell CJ, de Bakker PI: SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap. Bioinformatics 2008;24:2938-2939 (PubMed ID Number: 18974171 PMCID: PMC2720775).

Kalichman L, Li L, Kim DH, Guermazi A, Berkin V, O’Donnell CJ, Hoffmann U, Cole R, Hunter DJ. Facet joint osteoarthritis and low back pain in the community-based population. Spine. 2008 Nov 1;33(23):2560-5. (PubMed ID Number: 18923337).

Kalmbach RD, Choumenkovitch SF, Troen AM, D’Agostino R, Jacques PF, Selhub J: Circulating folic acid in plasma: relation to folic acid fortification. Am J Clin Nutr 2008;88:763-768 (PubMed ID Number: 18779294).

Kalmbach RD, Choumenkovitch SF, Troen AP, Jacques PF, D’Agostino R, Selhub J: A 19-base pair deletion polymorphism in dihydrofolate reductase is associated with increased unmetabolized folic acid in plasma and decreased red blood cell folate. J Nutr 2008;138:2323-2327 (PubMed ID Number: 19022952 PMCID: PMC2855991).

Kannel WB, Benjamin EJ: Status of the epidemiology of atrial fibrillation. Med Clin North Am 2008;92:17-40, ix (PubMed ID Number: 18060995 PMCID: PMC2245891).

Kannel WB, Evans JC, Piper S, Murabito JM: Angina pectoris is a stronger indicator of diffuse vascular atherosclerosis than intermittent claudication: Framingham study. J Clin Epidemiol 2008;61:951-957 (PubMed ID Number: 18495425).

Kannel WB, Vasan RS, Keyes MJ, Sullivan LM, Robins SJ: Usefulness of the triglyceride-high-density lipoprotein versus the cholesterol-high-density lipoprotein ratio for predicting insulin resistance and cardiometabolic risk (from the Framingham Offspring Cohort). Am J Cardiol 2008;101:497-501 (PubMed ID Number: 18312765).

Kannel WB, Wolf PA: Framingham study insights on the hazards of elevated blood pressure. JAMA 2008;300:2545-2547 (PubMed ID Number: 19050198).

Karasik D, Shimabuku NA, Zhou Y, Zhang Y, Cupples LA, Kiel DP, Demissie S: A genome wide linkage scan of metacarpal size and geometry in the Framingham Study. Am J Hum Biol 2008;20:663-670 (PubMed ID Number: 18449921 PMCID: PMC2574919).

Keaney JF, Jr., Lipinska I, Larson MG, Dupuis J, Freedman JE, Hamburg NM, Massaro JM, Rong J, Sutherland P, Vita JA, Vasan RS, Benjamin EJ: Clinical correlates, heritability, and genetic linkage of circulating CD40 ligand in the Framingham Offspring Study. Am Heart J 2008;156:1003-1009 (PubMed ID Number: 19061720 PMCID: PMC2613323).

Kimura M, Cherkas LF, Kato BS, Demissie S, Hjelmborg JB, Brimacombe M, Cupples A, Hunkin JL, Gardner JP, Lu X, Cao X, Sastrasinh M, Province MA, Hunt SC, Christensen K, Levy D, Spector TD, Aviv A: Offspring’s Leukocyte Telomere Length, Paternal Age, and Telomere Elongation in Sperm. PLoS Genet 2008;4:e37 (PubMed ID Number: 18282113 PMCID: PMC2242810).

Kottgen A, Hwang SJ, Rampersaud E, Coresh J, North KE, Pankow JS, Meigs JB, Florez JC, Parsa A, Levy D, Boerwinkle E, Shuldiner AR, Fox CS, Kao WH: TCF7L2 variants associate with CKD progression and renal function in population-based cohorts. J Am Soc Nephrol 2008;19:1989-1999 (PubMed ID Number: 18650481 PMCID: PMC2551569).

Kottgen A, Kao WH, Hwang SJ, Boerwinkle E, Yang Q, Levy D, Benjamin EJ, Larson MG, Astor BC, Coresh J, Fox CS: Genome-wide association study for renal traits in the Framingham Heart and Atherosclerosis Risk in Communities Studies. BMC Med Genet 2008;9:49 (PubMed ID Number: 18522750 PMCID: PMC2430944).

Lago RM, Pencina MJ, Wang TJ, Lanier KJ, D’Agostino RB, Kannel WB, Vasan RS: Interindividual variation in serum sodium and longitudinal blood pressure tracking in the Framingham Heart Study. J Hypertens 2008;26:2121-2125 (PubMed ID Number: 18854750 PMCID: PMC2654385).

Lamon-Fava S, Herrington DM, Reboussin DM, Sherman M, Horvath KV, Cupples LA, White C, Demissie S, Schaefer EJ, Asztalos BF: Plasma levels of HDL subpopulations and remnant lipoproteins predict the extent of angiographically-defined coronary artery disease in postmenopausal women. Arterioscler Thromb Vasc Biol 2008;28:575-579 (PubMed ID Number: 18174456).

Larson MG: Analysis of variance. Circulation 2008;117:115-121 (PubMed ID Number: 18172051).

Lasky-Su J, Lyon HN, Emilsson V, Heid IM, Molony C, Raby BA, Lazarus R, Klanderman B, Soto-Quiros ME, Avila L, Silverman EK, Thorleifsson G, Thorsteinsdottir U, Kronenberg F, Vollmert C, Illig T, Fox CS, Levy D, Laird N, Ding X, McQueen MB, Butler J, Ardlie K, Papoutsakis C, Dedoussis G, O’Donnell CJ, Wichmann HE, Celedon JC, Schadt E, Hirschhorn J, Weiss ST, Stefansson K, Lange C: On the replication of genetic associations: timing can be everything! Am J Hum Genet 2008;82:849-858 (PubMed ID Number: 18387595 PMCID: PMC2427263).

Lee DS, Larson MG, Lunetta KL, Dupuis J, Rong J, Keaney JF, Jr., Lipinska I, Baldwin CT, Vasan RS, Benjamin EJ: Clinical and genetic correlates of soluble P-selectin in the community. J Thromb Haemost 2008;6:20-31 (PubMed ID Number: 17944986).

Levitzky YS, Cupples LA, Murabito JM, Kannel WB, Kiel DP, Wilson PW, Wolf PA, O’Donnell CJ: Prediction of intermittent claudication, ischemic stroke, and other cardiovascular disease by detection of abdominal aortic calcific deposits by plain lumbar radiographs. Am J Cardiol 2008;101:326-331 (PubMed ID Number: 18237594).

Levitzky YS, Guo CY, Rong J, Larson MG, Walter RE, Keaney JF, Jr., Sutherland PA, Vasan A, Lipinska I, Evans JC, Benjamin EJ: Relation of smoking status to a panel of inflammatory markers: The Framingham offspring. Atherosclerosis 2008;201:217-224 (PubMed ID Number: 18289552 PMCID: PMC2783981).

Levitzky YS, Pencina MJ, D’Agostino RB, Meigs JB, Murabito JM, Vasan RS, Fox CS: Impact of impaired fasting glucose on cardiovascular disease: the Framingham Heart Study. J Am Coll Cardiol 2008;51:264-270 (PubMed ID Number: 18206734).

Lewis GD, Gona P, Larson MG, Plehn JF, Benjamin EJ, O’Donnell CJ, Levy D, Vasan RS, Wang TJ: Exercise blood pressure and the risk of incident cardiovascular disease (from the Framingham Heart Study). Am J Cardiol 2008;101:1614-1620 (PubMed ID Number: 18489939).

Lieb W, Pencina MJ, Wang TJ, Larson MG, Lanier KJ, Benjamin EJ, Levy D, Tofler GH, Meigs JB, Newton-Cheh C, Vasan RS: Association of parental hypertension with concentrations of select biomarkers in nonhypertensive offspring. Hypertension 2008;52:381-386 (PubMed ID Number: 18574071 PMCID: PMC2574605).

Lo GH, Niu J, McLennan CE, Kiel DP, McLean RR, Guermazi A, Genant HK, McAlindon TE, Hunter DJ: Meniscal damage associated with increased local subchondral bone mineral density: a Framingham study. Osteoarthritis Cartilage 2008;16:261-267 (PubMed ID Number: 17825586 PMCID: PMC2278381).

Loomba R, Hwang SJ, O’Donnell CJ, Ellison RC, Vasan RS, D’Agostino RB, Sr., Liang TJ, Fox CS: Parental obesity and offspring serum alanine and aspartate aminotransferase levels: the framingham heart study. Gastroenterology 2008;134:953-959 (PubMed ID Number: 18395076 PMCID: PMC2709779).

Maia AL, Hwang SJ, Levy D, Larson MG, Larsen PR, Fox CS: Lack of association between the type 2 deiodinase A/G polymorphism and hypertensive traits: the Framingham Heart Study. Hypertension 2008;51:e22-e23 (PubMed ID Number: 18285610).

McArdle PF, Rutherford S, Mitchell BD, Damcott CM, Wang Y, Ramachandran V, Ott S, Chang YP, Levy D, Steinle N: Nicotinic acetylcholine receptor subunit variants are associated with blood pressure; findings in the Old Order Amish and replication in the Framingham Heart Study. BMC Med Genet 2008;9:67 (PubMed ID Number: 18625075 PMCID: PMC2478679).

McCarthy EP, Pencina MJ, Kelly-Hayes M, Evans JC, Oberacker EJ, D’Agostino RB, Sr., Burns RB, Murabito JM: Advance care planning and health care preferences of community-dwelling elders: the framingham heart study. J Gerontol A Biol Sci Med Sci 2008;63:951-959 (PubMed ID Number: 18840800 PMCID: PMC2693192).

McLean RR, Jacques PF, Selhub J, Fredman L, Tucker KL, Samelson EJ, Kiel DP, Cupples LA, Hannan MT: Plasma B vitamins, homocysteine, and their relation with bone loss and hip fracture in elderly men and women. J Clin Endocrinol Metab 2008;93:2206-2212 (PubMed ID Number: 18364381 PMCID: PMC2435634).

Meigs JB, Manning AK, Dupuis J, Liu C, Florez JC, Adrienne CL: Ordered stratification to reduce heterogeneity in linkage to diabetes-related quantitative traits. Obesity (Silver Spring) 2008;16:2314-2322 (PubMed ID Number: 18719643).

Meigs JB, Shrader P, Sullivan LM, McAteer JB, Fox CS, Dupuis J, Manning AK, Florez JC, Wilson PW, D’Agostino RB, Sr., Cupples LA: Genotype score in addition to common risk factors for prediction of type 2 diabetes. N Engl J Med 2008;359:2208-2219 (PubMed ID Number: 19020323 PMCID: PMC2746946).

Molenaar EA, Hwang SJ, Vasan RS, Grobbee DE, Meigs JB, D’Agostino RB, Sr., Levy D, Fox CS: Burden and rates of treatment and control of cardiovascular disease risk factors in obesity: the Framingham Heart Study. Diabetes Care 2008;31:1367-1372 (PubMed ID Number: 18375414 PMCID: PMC2453683).

Murabito JM, Pencina MJ, Zhu L, Kelly-Hayes M, Shrader P, D’Agostino RB, Sr.: Temporal trends in self-reported functional limitations and physical disability among the community-dwelling elderly population: the Framingham heart study. Am J Public Health 2008;98:1256-1262 (PubMed ID Number: 18511716 PMCID: PMC2424084).

O’Donnell CJ, Demissie S, Kimura M, Levy D, Gardner JP, White C, D’Agostino RB, Wolf PA, Polak J, Cupples LA, Aviv A: Leukocyte telomere length and carotid artery intimal medial thickness: the Framingham Heart Study. Arterioscler Thromb Vasc Biol 2008;28:1165-1171 (PubMed ID Number: 18388332).

O’Donnell CJ, Elosua R: [Cardiovascular risk factors. Insights from Framingham Heart Study]. Rev Esp Cardiol 2008;61:299-310 (PubMed ID Number: 18361904).

Oyama N, Gona P, Salton CJ, Chuang ML, Jhaveri RR, Blease SJ, Manning AR, Lahiri M, Botnar RM, Levy D, Larson MG, O’Donnell CJ, Manning WJ: Differential impact of age, sex, and hypertension on aortic atherosclerosis: the Framingham Heart Study. Arterioscler Thromb Vasc Biol 2008;28:155-159 (PubMed ID Number: 17991874).

Pani LN, Korenda L, Meigs JB, Driver C, Chamany S, Fox CS, Sullivan L, D’Agostino RB, Nathan DM: Effect of aging on A1C levels in individuals without diabetes: evidence from the Framingham Offspring Study and the National Health and Nutrition Examination Survey 2001-2004. Diabetes Care 2008;31:1991-1996 (PubMed ID Number: 18628569 PMCID: PMC2551641).

Parikh NI, Hwang SJ, Larson MG, Hoffmann U, Levy D, Meigs JB, O’Donnell CJ, Fox CS: Indexes of kidney function and coronary artery and abdominal aortic calcium (from the Framingham Offspring Study). Am J Cardiol 2008;102:440-443 (PubMed ID Number: 18678302 PMCID: PMC2709777).

Parikh NI, Hwang SJ, Larson MG, Levy D, Fox CS: Chronic kidney disease as a predictor of cardiovascular disease (from the Framingham Heart Study). Am J Cardiol 2008;102:47-53 (PubMed ID Number: 18572034 PMCID: PMC2517213).

Parikh NI, Hwang SJ, Yang Q, Larson MG, Guo CY, Robins SJ, Sutherland P, Benjamin EJ, Levy D, Fox CS: Clinical correlates and heritability of cystatin C (from the Framingham Offspring Study). Am J Cardiol 2008;102:1194-1198 (PubMed ID Number: 18940290 PMCID: PMC2709776).

Parikh NI, Pencina MJ, Wang TJ, Benjamin EJ, Lanier KJ, Levy D, D’Agostino RB, Sr., Kannel WB, Vasan RS: A risk score for predicting near-term incidence of hypertension: the Framingham Heart Study. Ann Intern Med 2008;148:102-110 (PubMed ID Number: 18195335).

Paul CA, Au R, Fredman L, Massaro JM, Seshadri S, DeCarli C, Wolf PA: Association of alcohol consumption with brain volume in the Framingham study. Arch Neurol 2008;65:1363-1367 (PubMed ID Number: 18852353 PMCID: PMC2861346).

Pearce EN, Wilson PW, Yang Q, Vasan RS, Braverman LE: Thyroid function and lipid subparticle sizes in patients with short-term hypothyroidism and a population-based cohort. J Clin Endocrinol Metab. 2008 Mar;93(3)888-94. Epub 2007 Dec 11. (PubMed ID Number: 18073305; Abstract).

Pencina MJ, D’Agostino RB, Sr., D’Agostino RB, Jr., Vasan RS: Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond. Stat Med 2008;27:157-172 (PubMed ID Number: 17569110).

Pencina MJ, Millen BE, Hayes LJ, D’Agostino RB: Performance of a method for identifying the unique dietary patterns of adult women and men: the Framingham nutrition studies. J Am Diet Assoc 2008;108:1453-1460 (PubMed ID Number: 18755317 PMCID: PMC2586068).

Peter I, Kelley-Hedgepeth A, Fox CS, Cupples LA, Huggins GS, Housman DE, Karas RH, Mendelsohn ME, Levy D, Murabito JM: Variation in estrogen-related genes associated with cardiovascular phenotypes and circulating estradiol, testosterone, and dehydroepiandrosterone sulfate levels. J Clin Endocrinol Metab 2008;93:2779-2785 (PubMed ID Number: 18445666 PMCID: PMC2453049).

Romero JR, Morris J, Pikula A: Stroke prevention: modifying risk factors. Ther Adv Cardiovasc Dis. 2008 Aug;2(4):287-303. (PubMed ID Number: 19124428. PMCID: PMC2729177).

Romero JR, Vasan RS, Beiser AS, Polak JF, Benjamin EJ, Wolf PA, Seshadri S: Association of carotid artery atherosclerosis with circulating biomarkers of extracellular matrix remodeling: the Framingham Offspring Study. J Stroke Cerebrovasc Dis 2008;17:412-417 (PubMed ID Number: 18984437 PMCID: PMC2613480).

Rosito GA, Massaro JM, Hoffmann U, Ruberg FL, Mahabadi AA, Vasan RS, O’Donnell CJ, Fox CS: Pericardial fat, visceral abdominal fat, cardiovascular disease risk factors, and vascular calcification in a community-based sample: the Framingham Heart Study. Circulation 2008;117:605-613 (PubMed ID Number: 18212276).

Rutter MK, Wilson PW, Sullivan LM, Fox CS, D’Agostino RB, Sr., Meigs JB: Use of alternative thresholds defining insulin resistance to predict incident type 2 diabetes mellitus and cardiovascular disease. Circulation 2008;117:1003-1009 (PubMed ID Number: 18250267 PMCID: PMC2519012).

Sahni S, Hannan MT, Gagnon D, Blumberg J, Cupples LA, Kiel DP, Tucker KL: High vitamin C intake is associated with lower 4-year bone loss in elderly men. J Nutr 2008;138:1931-1938 (PubMed ID Number: 18806103 PMCID: PMC2752366).

Samelson EJ, Broe KE, Demissie S, Beck TJ, Karasik D, Kathiresan S, Kiel DP: Increased plasma osteoprotegerin concentrations are associated with indices of bone strength of the hip. J Clin Endocrinol Metab 2008;93:1789-1795 (PubMed ID Number: 18303076 PMCID: PMC2386280).

Schnabel R, Larson MG, Dupuis J, Lunetta KL, Lipinska I, Meigs JB, Yin X, Rong J, Vita JA, Newton-Cheh C, Levy D, Keaney JF, Jr., Vasan RS, Mitchell GF, Benjamin EJ: Relations of inflammatory biomarkers and common genetic variants with arterial stiffness and wave reflection. Hypertension 2008;51:1651-1657 (PubMed ID Number: 18426996 PMCID: PMC2892983).

Seshadri S, Wolf PA, Beiser AS, Selhub J, Au R, Jacques PF, Yoshita M, Rosenberg IH, D’Agostino RB, DeCarli C: Association of plasma total homocysteine levels with subclinical brain injury: cerebral volumes, white matter hyperintensity, and silent brain infarcts at volumetric magnetic resonance imaging in the Framingham Offspring Study. Arch Neurol 2008;65:642-649 (PubMed ID Number: 18474741 PMCID: PMC2700952).

Shea MK, Booth SL, Massaro JM, Jacques PF, D’Agostino RB, Sr., wson-Hughes B, Ordovas JM, O’Donnell CJ, Kathiresan S, Keaney JF, Jr., Vasan RS, Benjamin EJ: Vitamin K and vitamin D status: associations with inflammatory markers in the Framingham Offspring Study. Am J Epidemiol 2008;167:313-320 (PubMed ID Number: 18006902).

Speliotes EK, Massaro JM, Hoffmann U, Foster MC, Sahani DV, Hirschhorn JN, O’Donnell CJ, Fox CS: Liver fat is reproducibly measured using computed tomography in the Framingham Heart Study. J Gastroenterol Hepatol 2008;23:894-899 (PubMed ID Number: 18565021).

Stolerman ES, Manning AK, McAteer JB, Dupuis J, Fox CS, Cupples LA, Meigs JB, Florez JC: Haplotype structure of the ENPP1 Gene and Nominal Association of the K121Q missense single nucleotide polymorphism with glycemic traits in the Framingham Heart Study. Diabetes 2008;57:1971-1977 (PubMed ID Number: 18426862 PMCID: PMC2453609).

Szekely CA, Green RC, Breitner JC, Ostbye T, Beiser AS, Corrada MM, Dodge HH, Ganguli M, Kawas CH, Kuller LH, Psaty BM, Resnick SM, Wolf PA, Zonderman AB, Welsh-Bohmer KA, Zandi PP: No advantage of A beta 42-lowering NSAIDs for prevention of Alzheimer dementia in six pooled cohort studies. Neurology 2008;70:2291-2298 (PubMed ID Number: 18509093 PMCID: PMC2755238).

Tan ZS, Beiser A, Vasan RS, Au R, Auerbach S, Kiel DP, Wolf PA, Seshadri S: Thyroid function and the risk of Alzheimer disease: the Framingham Study. Arch Intern Med 2008;168:1514-1520 (PubMed ID Number: 18663163 PMCID: PMC2694610).

Vasan RS, Demissie S, Kimura M, Cupples LA, Rifai N, White C, Wang TJ, Gardner JP, Cao X, Benjamin EJ, Levy D, Aviv A: Association of leukocyte telomere length with circulating biomarkers of the renin-angiotensin-aldosterone system: the Framingham Heart Study. Circulation 2008;117:1138-1144 (PubMed ID Number: 18268147).

Velagaleti RS, Gona P, Levy D, Aragam J, Larson MG, Tofler GH, Lieb W, Wang TJ, Benjamin EJ, Vasan RS: Relations of biomarkers representing distinct biological pathways to left ventricular geometry. Circulation 2008;118:2252-8, 5p (PubMed ID Number: 19001021 PMCID: PMC2747641).

Velagaleti RS, Pencina MJ, Murabito JM, Wang TJ, Parikh NI, D’Agostino RB, Levy D, Kannel WB, Vasan RS: Long-term trends in the incidence of heart failure after myocardial infarction. Circulation 2008;118:2057-2062 (PubMed ID Number: 18955667 PMCID: PMC2729712).

Walter RE, Wilk JB, Larson MG, Vasan RS, Keaney JF, Jr., Lipinska I, O’Connor GT, Benjamin EJ: Systemic inflammation and COPD: the Framingham Heart Study. Chest 2008;133:19-25 (PubMed ID Number: 17908709).

Wang TJ, Pencina MJ, Booth SL, Jacques PF, Ingelsson E, Lanier K, Benjamin EJ, D’Agostino RB, Wolf M, Vasan RS: Vitamin D deficiency and risk of cardiovascular disease. Circulation 2008;117:503-511 (PubMed ID Number: 18180395).

Wilson PW, Meigs JB: Cardiometabolic risk: a Framingham perspective. Int J Obes (Lond) 2008;32 Suppl 2:S17-S20 (PubMed ID Number: 18469835).

Young JA, Hwang SJ, Sarnak MJ, Hoffmann U, Massaro JM, Levy D, Benjamin EJ, Larson MG, Vasan RS, O’Donnell CJ, Fox CS: Association of visceral and subcutaneous adiposity with kidney function. Clin J Am Soc Nephrol. 2008 Nov;3(6):1786-91. Epub 2008 Sep 24 (PubMed ID Number: 18815239 PMCID: PMC2572280).

Yoshida M, Booth SL, Meigs JB, Saltzman E, Jacques PF: Phylloquinone intake, insulin sensitivity, and glycemic status in men and women. Am J Clin Nutr 2008;88:210-215 (PubMed ID Number: 18614743).

Zhang Y, Guo X, Saitz R, Levy D, Sartini E, Niu J, Ellison RC: Secular trends in alcohol consumption over 50 years: the Framingham Study. Am J Med 2008;121:695-701 (PubMed ID Number: 18691483 PMCID: PMC2562028).

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