The Framingham Heart Study is a project of Boston University & the National Heart, Lung, & Blood Institute.
The Framingham Heart Study is a project of Boston University & the National Heart, Lung, & Blood Institute.

Framingham Heart Study Bibliography – 2007

Abdel-Qadir HM, Lee DS: The contribution of familial and heritable risks in heart failure. Curr Opin Cardiol 2007; 22(3):214-219. (PubMed ID Number: 17413278; Abstract).

Benjamin EJ, Dupuis J, Larson MG, Lunetta KL, Booth SL, Govindaraju DR, Kathiresan S, Keaney JF, Jr., Keyes MJ, Lin JP, Meigs JB, Robins SJ, Rong J, Schnabel R, Vita JA, Wang TJ, Wilson PW, Wolf PA, Vasan RS: Genome-wide association with select biomarker traits in the Framingham Heart Study. BMC Med Genet 2007; 8 Suppl 1:S11. (PubMed ID Number: 17903293; Abstract)

Berry SD, Samelson EJ, Hannan MT, McLean RR, Lu M, Cupples LA, Shaffer ML, Beiser AL, Kelly-Hayes M, Kiel DP: Second hip fracture in older men and women: the Framingham Study. Arch Intern Med 2007; 167(18):1971-1976. (PubMed ID Number: 17923597; Abstract)

Carandang R, Wolf PA: Trends in stroke over the past 50 years: the Framingham Study. Cardiology Review 2007; 24(8):23-25.

Chen MH, Cui J, Guo CY, Cupples LA, Van EP, Dupuis J, Yang Q: Joint modeling of linkage and association using affected sib-pair data. BMC Proc 2007;1 Suppl 1:S38 (PubMed ID Number: 18466536; Free Full Text).

Cho K, Yang Q, Dupuis J: Handling linkage disequilibrium in linkage analysis using dense single-nucleotide polymorphisms. BMC Proc 2007;1 Suppl 1:S161 (PubMed ID Number: 18466507; Free Full Text).

Christakis NA, Fowler JH: The spread of obesity in a large social network over 32 years. N Engl J Med 2007; 357(4):370-379. (PubMed ID Number: 17652652; Abstract)

Cobain MR, Pencina MJ, D’Agostino RB, Sr., Vasan RS: Lifetime risk for developing dyslipidemia: the Framingham Offspring Study. Am J Med 2007; 120(7):623-630. (PubMed ID Number: 17602937; Abstract)

Corella D, Lai CQ, Demissie S, Cupples LA, Manning AK, Tucker KL, Ordovas JM: APOA5 gene variation modulates the effects of dietary fat intake on body mass index and obesity risk in the Framingham Heart Study. J Mol Med 2007; 85(2):119-128. (PubMed ID Number: 17211608; Abstract)

Cupples LA, Arruda HT, Benjamin EJ, D’Agostino RB, Sr., Demissie S, DeStefano AL, Dupuis J, Falls KM, Fox CS, Gottlieb DJ, Govindaraju DR, Guo CY, Heard-Costa NL, Hwang SJ, Kathiresan S, Kiel DP, Laramie JM, Larson MG, Levy D, Liu CY, Lunetta KL, Mailman MD, Manning AK, Meigs JB, Murabito JM, Newton-Cheh C, O’connor GT, O’Donnell CJ, Pandey M, Seshadri S, Vasan RS, Wang ZY, Wilk JB, Wolf PA, Yang Q, Atwood LD: The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports. BMC Med Genet 2007; 8 Suppl 1:S1. (PubMed ID Number: 17903291; Abstract)

Demissie S, Dupuis J, Cupples LA, Beck TJ, Kiel DP, Karasik D: Proximal hip geometry is linked to several chromosomal regions: genome-wide linkage results from the Framingham Osteoporosis Study. Bone 2007; 40(3):743-750. (PubMed ID Number: 17079199; Abstract)

Dhingra R, Gona P, Nam BH, D’Agostino RB Sr, Wilson PW, Benjamin EJ, O’Donnell CJ: C-reactive protein, inflammatory conditions, and cardiovascular disease risk. Am J Med. 2007 Dec;120(12):1054-62. (PubMed ID Number: 18060926; Abstract)

Dhingra R, Sullivan L, Jacques PF, Wang TJ, Fox CS, Meigs JB, D’Agostino RB, Gaziano JM, Vasan RS: Soft drink consumption and risk of developing cardiometabolic risk factors and the metabolic syndrome in middle-aged adults in the community. Circulation 2007; 116(5):480-488 (PubMed ID Number: 17646581; Abstract)

Dhingra R, Sullivan LM, Fox CS, Wang TJ, D’Agostino RB, Sr., Gaziano JM, Vasan RS: Relations of serum phosphorus and calcium levels to the incidence of cardiovascular disease in the community. Arch Intern Med 2007; 167(9):879-885 (PubMed ID Number: 17502528; Abstract)

Djousse L, Karamohamed S, Herbert AG, D’Agostino RB, Cupples LA, Ellison RC: Fucosyltransferase 3 polymorphism and atherothrombotic disease in the Framingham Offspring Study. Am Heart J 2007; 153(4):636-639 488 (PubMed ID Number: 17383304; Abstract)

Eaker ED, Sullivan LM, Kelly-Hayes M, D’Agostino RB, Sr., Benjamin EJ: Marital status, marital strain, and risk of coronary heart disease or total mortality: the Framingham Offspring Study. Psychosom Med 2007; 69(6):509-513 (PubMed ID Number: 17634565. no Abstract)

Elias MF, Sullivan LM, Elias PK, D’Agostino RB, Sr., Wolf PA, Seshadri S, Au R, Benjamin EJ, Vasan RS: Left ventricular mass, blood pressure, and lowered cognitive performance in the Framingham offspring. Hypertension 2007; 49(3):439-445 (PubMed ID Number: 17224472; Abstract)

Felson DT, Niu J, Clancy M, Aliabadi P, Sack B, Guermazi A, Hunter DJ, Amin S, Rogers G, Booth SL: Low levels of vitamin D and worsening of knee osteoarthritis: results of two longitudinal studies. Arthritis Rheum 2007; 56(1):129-136 445 (PubMed ID Number: 17195215; Abstract)

Felson DT, Niu J, Clancy M, Sack B, Aliabadi P, Zhang Y: Effect of recreational physical activities on the development of knee osteoarthritis in older adults of different weights: the Framingham Study. Arthritis Rheum 2007; 57(1):6-12 445 (PubMed ID Number: 17266077; Abstract)

Felson DT, Niu J, McClennan C, Sack B, Aliabadi P, Hunter DJ, Guermazi A, Englund M: Knee buckling: prevalence, risk factors, and associated limitations in function. Ann Intern Med 2007; 147(8):534-540 445 (PubMed ID Number: 17938391; Abstract)

Florez JC, Manning AK, Dupuis J, McAteer J, Irenze K, Gianniny L, Mirel DB, Fox CS, Cupples LA, Meigs JB: A 100K genome-wide association scan for diabetes and related traits in the Framingham Heart Study: replication and integration with other genome-wide datasets. Diabetes. 2007 Dec;56(12):3063-74. Epub 2007 Sep 11. (PubMed ID Number: 17848626; Abstract)

Fogli-Cawley JJ, Dwyer JT, Saltzman E, McCullough ML, Troy LM, Meigs JB, Jacques PF: The 2005 Dietary Guidelines for Americans and risk of the metabolic syndrome. Am J Clin Nutr 2007; 86(4):1193-1201 . (PubMed ID Number: 17921402; Abstract)

Fogli-Cawley JJ, Dwyer JT, Saltzman E, McCullough ML, Troy LM, Meigs JB, Jacques PF: The 2005 Dietary Guidelines for Americans and insulin resistance in the Framingham Offspring Cohort. Diabetes Care 2007; 30(4):817-822 . (PubMed ID Number: 17259479; Abstract)

Foster MC, Hwang SJ, Larson MG, Parikh NI, Meigs JB, Vasan RS, Wang TJ, Levy D, Fox CS: Cross-classification of microalbuminuria and reduced glomerular filtration rate: associations between cardiovascular disease risk factors and clinical outcomes. Arch Intern Med 2007; 167(13):1386-1392 . (PubMed ID Number: 17620532; Abstract)

Fox CS, Coady S, Sorlie PD, D’Agostino RB, Sr., Pencina MJ, Vasan RS, Meigs JB, Levy D, Savage PJ: Increasing cardiovascular disease burden due to diabetes mellitus: the Framingham Heart Study. Circulation 2007; 115(12):1544-1550. (PubMed ID Number: 17353438; Abstract)

Fox CS, Heard-Costa N, Cupples LA, Dupuis J, Vasan RS, Atwood LD: Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project. BMC Med Genet 2007; 8 Suppl 1:S18 . (PubMed ID Number: 17903300; Abstract)

Fox CS, Massaro JM, Hoffmann U, Pou KM, Maurovich-Horvat P, Liu CY, Vasan RS, Murabito JM, Meigs JB, Cupples LA, D’Agostino RB, Sr., O’Donnell CJ: Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham Heart Study. Circulation 2007; 116(1):39-48 . (PubMed ID Number: 17576866; Abstract)

Gottlieb DJ, O’connor GT, Wilk JB: Genome-wide association of sleep and circadian phenotypes. BMC Med Genet 2007; 8 Suppl 1:S9 . (PubMed ID Number: 17903308; Abstract)

Gross KD, Niu J, Zhang YQ, Felson DT, McLennan C, Hannan MT, Holt KG, Hunter DJ: Varus foot alignment and hip conditions in older adults. Arthritis Rheum 2007; 56(9):2993-2998 . (PubMed ID Number: 17763430; Abstract)

Guo CY, Lunetta KL, DeStefano AL, Ordovas JM, Cupples LA: Informative-transmission disequilibrium test (i-TDT): combined linkage and association mapping that includes unaffected offspring as well as affected offspring. Genet Epidemiol 2007; 31(2):115-133 . (PubMed ID Number: 17123304; Abstract)

Guo CY: The impact of complex informative missingness on the validity of the transmission/disequilibrium test (TDT). BMC Proc 2007;1 Suppl 1:S26 (PubMed ID Number: 18466523.

Herbert A, Lenburg ME, Ulrich D, Gerry NP, Schlauch K, Christman MF: Open-access database of candidate associations from a genome-wide SNP scan of the Framingham Heart Study. Nat Genet 2007; 39(2):135-136 . (PubMed ID Number: 17262019; No Abstract)

Hunter DJ, Niu J, Felson DT, Harvey WF, Gross KD, McCree P, Aliabadi P, Sack B, Zhang Y: Knee alignment does not predict incident osteoarthritis: the Framingham osteoarthritis study. Arthritis Rheum 2007; 56(4):1212-1218 (PubMed ID Number: 17393450; Abstract)

Hwang SJ, Yang Q, Meigs JB, Pearce EN, Fox CS: A genome-wide association for kidney function and endocrine-related traits in the NHLBI’s Framingham Heart Study. BMC Med Genet 2007; 8 Suppl 1:S10 (PubMed ID Number: 17903292; Abstract)

Ingelsson E, Larson MG, Fox CS, Yin X, Wang TJ, Lipinska I, Pou KM, Hoffmann U, Benjamin EJ, Keaney JF, Jr., Vasan RS: Clinical correlates of circulating visfatin levels in a community-based sample. Diabetes Care 2007; 30(5):1278-1280 (PubMed ID Number: 17261750; No Abstract)

Ingelsson E, Larson MG, Vasan RS, O’Donnell CJ, Yin X, Hirschhorn JN, Newton-Cheh C, Drake JA, Musone SL, Heard-Costa NL, Benjamin EJ, Levy D, Atwood LD, Wang TJ, Kathiresan S: Heritability, linkage, and genetic associations of exercise treadmill test responses. Circulation 2007; 115(23):2917-2924 (PubMed ID Number: 17548724; Abstract)

Ingelsson E, Pencina MJ, Tofler GH, Benjamin EJ, Lanier KJ, Jacques PF, Fox CS, Meigs JB, Levy D, Larson MG, Selhub J, D’Agostino RB, Sr., Wang TJ, Vasan RS: Multimarker approach to evaluate the incidence of the metabolic syndrome and longitudinal changes in metabolic risk factors: the Framingham Offspring Study. Circulation 2007; 116(9):984-992 (PubMed ID Number: 17698726; Abstract)

Ingelsson E, Schaefer EJ, Contois JH, McNamara JR, Sullivan L, Keyes MJ, Pencina MJ, Schoonmaker C, Wilson PW, D’Agostino RB, Vasan RS: Clinical utility of different lipid measures for prediction of coronary heart disease in men and women. JAMA 2007; 298(7):776-785 (PubMed ID Number: 17699011; Abstract)

Ingelsson E, Sullivan LM, Fox CS, Murabito JM, Benjamin EJ, Polak JF, Meigs JB, Keyes MJ, O’Donnell CJ, Wang TJ, D’Agostino RB, Wolf PA, Vasan RS: Burden and prognostic importance of subclinical cardiovascular disease in overweight and obese individuals. Circulation 2007; 116(4):375-384 (PubMed ID Number: 17620505; Abstract)

Ingelsson E, Sullivan LM, Murabito JM, Fox CS, Benjamin EJ, Polak JF, Meigs JB, Keyes MJ, O’Donnell CJ, Wang TJ, D’Agostino RB, Sr., Wolf PA, Vasan RS: Prevalence and prognostic impact of subclinical cardiovascular disease in individuals with the metabolic syndrome and diabetes. Diabetes 2007; 56(6):1718-1726 (PubMed ID Number: 17369522; Abstract)

Ioannidis JP, Ng MY, Sham PC, Zintzaras E, Lewis CM, Deng HW, Econs MJ, Karasik D, Devoto M, Kammerer CM, Spector T, Andrew T, Cupples LA, Duncan EL, Foroud T, Kiel DP, Koller D, Langdahl B, Mitchell BD, Peacock M, Recker R, Shen H, Sol-Church K, Spotila LD, Uitterlinden AG, Wilson SG, Kung AW, Ralston SH: Meta-analysis of genome-wide scans provides evidence for sex- and site-specific regulation of bone mass. J Bone Miner Res 2007; 22(2):173-183 (PubMed ID Number: 17228994; Abstract)

Jefferson AL, Massaro JM, Wolf PA, Seshadri S, Au R, Vasan RS, Larson MG, Meigs JB, Keaney JF, Jr., Lipinska I, Kathiresan S, Benjamin EJ, DeCarli C: Inflammatory biomarkers are associated with total brain volume: the Framingham Heart Study. Neurology 2007; 68(13):1032-1038 (PubMed ID Number: 17389308; Abstract)

Karasik D, Dupuis J, Cupples LA, Beck TJ, Mahaney MC, Havill LM, Kiel DP, Demissie S: Bivariate linkage study of proximal hip geometry and body size indices: the Framingham Study. Calcif Tissue Int 2007; 81(3):162-173 (PubMed ID Number: 17674073; Abstract)

Kathiresan S, Larson MG, Keyes MJ, Polak JF, Wolf PA, D’Agostino RB, Jaffer FA, Clouse ME, Levy D, Manning WJ, O’Donnell CJ: Assessment by cardiovascular magnetic resonance, electron beam computed tomography, and carotid ultrasonography of the distribution of subclinical atherosclerosis across Framingham risk strata. Am J Cardiol 2007; 99(3):310-314 (PubMed ID Number: 17261388; Abstract)

Kathiresan S, Manning AK, Demissie S, D’Agostino RB, Surti A, Guiducci C, Gianniny L, Burtt NP, Melander O, Orho-Melander M, Arnett DK, Peloso GM, Ordovas JM, Cupples LA: A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. BMC Med Genet 2007; 8 Suppl 1:S17 (PubMed ID Number: 17903299; Abstract)

Kiel DP, Demissie S, Dupuis J, Lunetta KL, Murabito JM, Karasik D: Genome-wide association with bone mass and geometry in the Framingham Heart Study. BMC Med Genet 2007; 8 Suppl 1:S14 (PubMed ID Number: 17903296; Abstract)

Kiel DP, Ferrari SL, Cupples LA, Karasik D, Manen D, Imamovic A, Herbert AG, Dupuis J: Genetic variation at the low-density lipoprotein receptor-related protein 5 (LRP5) locus modulates Wnt signaling and the relationship of physical activity with bone mineral density in men. Bone 2007; 40(3):587-596 (PubMed ID Number: 17137849; Abstract)

Larson MG, Atwood LD, Benjamin EJ, Cupples LA, D’Agostino RB, Sr., Fox CS, Govindaraju DR, Guo CY, Heard-Costa NL, Hwang SJ, Murabito JM, Newton-Cheh C, O’Donnell CJ, Seshadri S, Vasan RS, Wang TJ, Wolf PA, Levy D: Framingham Heart Study 100K project: genome-wide associations for cardiovascular disease outcomes. BMC Med Genet 2007; 8 Suppl 1:S5 (PubMed ID Number: 17903304; Abstract)

Lee DS, Evans JC, Robins SJ, Wilson PW, Albano I, Fox CS, Wang TJ, Benjamin EJ, D’Agostino RB, Vasan RS: Gamma glutamyl transferase and metabolic syndrome, cardiovascular disease, and mortality risk: the Framingham Heart Study. Arterioscler Thromb Vasc Biol 2007; 27(1):127-133 (PubMed ID Number: 17095717; Abstract)

Lee DS, Massaro JM, Wang TJ, Kannel WB, Benjamin EJ, Kenchaiah S, Levy D, D’Agostino RB, Sr., Vasan RS: Antecedent blood pressure, body mass index, and the risk of incident heart failure in later life. Hypertension 2007; 50(5):869-876 (PubMed ID Number: 17893376; Abstract)

Lessov-Schlaggar CN, Swan GE, Reed T, Wolf PA, Carmelli D: Longitudinal genetic analysis of executive function in elderly men. Neurobiol Aging 2007; 28(11):1759-1768 (PubMed ID Number: 16965841; Abstract)

Levy D, Hwang SJ, Kayalar A, Benjamin EJ, Vasan RS, Parise H, Larson MG, Wang TJ, Selhub J, Jacques PF, Vita JA, Keyes MJ, Mitchell GF: Associations of plasma natriuretic peptide, adrenomedullin, and homocysteine levels with alterations in arterial stiffness: the Framingham Heart Study. Circulation 2007; 115(24):3079-3085 (PubMed ID Number: 17533184; Abstract)

Levy D, Larson MG, Benjamin EJ, Newton-Cheh C, Wang TJ, Hwang SJ, Vasan RS, Mitchell GF: Framingham Heart Study 100K Project: genome-wide associations for blood pressure and arterial stiffness. BMC Med Genet 2007; 8 Suppl 1:S3 (PubMed ID Number: 17903302; Abstract)

Levy D: Hypertension from Framingham to ALLHAT: translating clinical trials into practice. Cleve Clin J Med 2007; 74(9):672-678 (PubMed ID Number: 17879521; Abstract)

Lin JP, O’Donnell CJ, Jin L, Fox C, Yang Q, Cupples LA: Evidence for linkage of red blood cell size and count: genome-wide scans in the Framingham Heart Study. Am J Hematol 2007; 82(7):605-610 (PubMed ID Number: 17211848; Abstract)

Lopez VA, Franklin SS, Tang S, Wong ND: Coronary heart disease events preventable by control of blood pressure and lipids in US adults with hypertension. J Clin Hypertens (Greenwich). 2007 Jun;9(6):436-43. (PubMed ID Number: 17541329; Abstract)

Lunetta KL, D’Agostino RB, Sr., Karasik D, Benjamin EJ, Guo CY, Govindaraju R, Kiel DP, Kelly-Hayes M, Massaro JM, Pencina MJ, Seshadri S, Murabito JM: Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study. BMC Med Genet 2007; 8 Suppl 1:S13 (PubMed ID Number: 17903295; Abstract)

Lyon HN, Emilsson V, Hinney A, Heid IM, Lasky-Su J, Zhu X, Thorleifsson G, Gunnarsdottir S, Walters GB, Thorsteinsdottir U, Kong A, Gulcher J, Nguyen TT, Scherag A, Pfeufer A, Meitinger T, Bronner G, Rief W, Soto-Quiros ME, Avila L, Klanderman B, Raby BA, Silverman EK, Weiss ST, Laird N, Ding X, Groop L, Tuomi T, Isomaa B, Bengtsson K, Butler JL, Cooper RS, Fox CS, O’Donnell CJ, Vollmert C, Celedon JC, Wichmann HE, Hebebrand J, Stefansson K, Lange C, Hirschhorn JN: The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts. PLoS Genet 2007; 3(4):e61 (PubMed ID Number: 17465681; Abstract)

Maia AL, Dupuis J, Manning A, Liu C, Meigs JB, Cupples LA, Larsen PR, Fox CS: The type 2 deiodinase (DIO2) A/G polymorphism is not associated with glycemic traits: the Framingham Heart Study. Thyroid 2007; 17(3):199-202 (PubMed ID Number: 17381351; Abstract)

Marrugat J, Subirana I, Comin E, Cabezas C, Vila J, Elosua R, Nam BH, Ramos R, Sala J, Solanas P, Cordon F, Gene-Badia J, D’Agostino RB: Validity of an adaptation of the Framingham cardiovascular risk function: the VERIFICA Study. J Epidemiol Community Health 2007; 61(1):40-47 (PubMed ID Number: 17183014; Abstract)

Maurovich-Horvat P, Massaro J, Fox CS, Moselewski F, O’Donnell CJ, Hoffmann U: Comparison of anthropometric, area- and volume-based assessment of abdominal subcutaneous and visceral adipose tissue volumes using multi-detector computed tomography. Int J Obes (Lond) 2007; 31(3):500-506(PubMed ID Number: 16953256; Abstract)

May M, Sterne JA, Shipley M, Brunner E, d’Agostino R, Whincup P, Ben-Shlomo Y, Carr A, Ledergerber B, Lundgren JD, Phillips AN, Massaro J, Egger M: A coronary heart disease risk model for predicting the effect of potent antiretroviral therapy in HIV-1 infected men. Int J Epidemiol. 2007 Dec;36(6):1309-18. Epub 2007 Jul 25. (PubMed ID Number: 17652317; Abstract)

Meigs JB, Larson MG, Fox CS, Keaney JF, Jr., Vasan RS, Benjamin EJ: Association of oxidative stress, insulin resistance, and diabetes risk phenotypes: the Framingham Offspring Study. Diabetes Care 2007; 30(10):2529-2535 (PubMed ID Number: 17586736; Abstract)

Meigs JB, Manning AK, Fox CS, Florez JC, Liu C, Cupples LA, Dupuis J: Genome-wide association with diabetes-related traits in the Framingham Heart Study. BMC Med Genet 2007; 8 Suppl 1:S16 (PubMed ID Number: 17903298; Abstract)

Meigs JB, Rutter MK, Sullivan LM, Fox CS, D’Agostino RB, Sr., Wilson PW: Impact of insulin resistance on risk of type 2 diabetes and cardiovascular disease in people with metabolic syndrome. Diabetes Care 2007; 30(5):1219-1225 (PubMed ID Number: 17259468; Abstract)

Meng Y, Yang Q, Cuenco KT, Cupples LA, DeStefano AL, Lunetta KL: Two-stage approach for identifying single-nucleotide polymorphisms associated with rheumatoid arthritis using random forests and Bayesian networks. BMC Proc 2007;1 Suppl 1:S56 (PubMed ID Number: 18466556; Free Full Text).

Mitchell GF, Guo CY, Benjamin EJ, Larson MG, Keyes MJ, Vita JA, Vasan RS, Levy D: Cross-sectional correlates of increased aortic stiffness in the community: the Framingham Heart Study. Circulation 2007; 115(20):2628-2636 (PubMed ID Number: 17485578; Abstract)

Mitchell GF, Guo CY, Kathiresan S, Vasan RS, Larson MG, Vita JA, Keyes MJ, Vyas M, Newton-Cheh C, Musone SL, Camargo AL, Drake JA, Levy D, O’Donnell CJ, Hirschhorn JN, Benjamin EJ: Vascular stiffness and genetic variation at the endothelial nitric oxide synthase locus: the Framingham Heart study. Hypertension 2007; 49(6):1285-1290 (PubMed ID Number: 17404185; Abstract)

Mitchell GF, Vasan RS, Keyes MJ, Parise H, Wang TJ, Larson MG, D’Agostino RB, Sr., Kannel WB, Levy D, Benjamin EJ: Pulse pressure and risk of new-onset atrial fibrillation. JAMA 2007; 297(7):709-715 (PubMed ID Number: 17312290; Abstract)

Murabito JM, Rosenberg CL, Finger D, Kreger BE, Levy D, Splansky GL, Antman K, Hwang SJ: A genome-wide association study of breast and prostate cancer in the NHLBI’s Framingham Heart Study. BMC Med Genet 2007; 8 Suppl 1:S6 (PubMed ID Number: 17903305; Abstract)

Newton-Cheh C, Guo CY, Gona P, Larson MG, Benjamin EJ, Wang TJ, Kathiresan S, O’Donnell CJ, Musone SL, Camargo AL, Drake JA, Levy D, Hirschhorn JN, Vasan RS: Clinical and genetic correlates of aldosterone-to-renin ratio and relations to blood pressure in a community sample. Hypertension 2007; 49(4):846-856 (PubMed ID Number: 17296870; Abstract)

Newton-Cheh C, Guo CY, Larson MG, Musone SL, Surti A, Camargo AL, Drake JA, Benjamin EJ, Levy D, D’Agostino RB, Sr., Hirschhorn JN, O’Donnell CJ: Common genetic variation in KCNH2 is associated with QT interval duration: the Framingham Heart Study. Circulation 2007; 116(10):1128-1136 (PubMed ID Number: 17709632; Abstract)

Newton-Cheh C, Guo CY, Wang TJ, O’Donnell CJ, Levy D, Larson MG: Genome-wide association study of electrocardiographic and heart rate variability traits: the Framingham Heart Study. BMC Med Genet 2007; 8 Suppl 1:S7 (PubMed ID Number: 17903306; Abstract)

O’Donnell CJ, Cupples LA, D’Agostino RB, Fox CS, Hoffmann U, Hwang SJ, Ingellson E, Liu C, Murabito JM, Polak JF, Wolf PA, Demissie S: Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI’s Framingham Heart Study. BMC Med Genet 2007; 8 Suppl 1:S4 (PubMed ID Number: 17903303; Abstract)

Parikh NI, Gona P, Larson MG, Wang TJ, Newton-Cheh C, Levy D, Benjamin EJ, Kannel WB, Vasan RS: Plasma renin and risk of cardiovascular disease and mortality: the Framingham Heart Study. Eur Heart J. 2007 Nov;28(21):2644-52. Epub 2007 Sep 25. (PubMed ID Number: 17895253; Abstract)

Parikh NI, Hwang SJ, Larson MG, Cupples LA, Fox CS, Manders ES, Murabito JM, Massaro JM, Hoffmann U, O’Donnell CJ: Parental occurrence of premature cardiovascular disease predicts increased coronary artery and abdominal aortic calcification in the Framingham Offspring and Third Generation cohorts. Circulation 2007; 116(13):1473-1481. (PubMed ID Number: 17785619; Abstract)

Parikh NI, Pencina MJ, Wang TJ, Lanier KJ, Fox CS, D’Agostino RB, Vasan RS: Increasing trends in incidence of overweight and obesity over 5 decades. Am J Med 2007; 120(3):242-250 (PubMed ID Number: 17349447; Abstract)

Parikh NI, Vasan RS: Assessing the clinical utility of biomarkers in medicine. [Review]. Biomarkers Med 2007;1:419-436. (PubMed ID Number: 20477384; Abstract)

Pencina MJ, D’Agostino RB, Beiser AS, Cobain MR, Vasan RS: Estimating lifetime risk of developing high serum total cholesterol: adjustment for baseline prevalence and single-occasion measurements. Am J Epidemiol 2007; 165(4):464-472. (PubMed ID Number: 17116649; Abstract)

Pencina MJ, Larson MG, D’Agostino RB: Choice of time scale and its effect on significance of predictors in longitudinal studies. Stat Med 2007; 26(6):1343-1359. (PubMed ID Number: 16955538; Abstract)

Peter I, Huggins GS, Shearman AM, Pollak A, Schmid CH, Cupples LA, Demissie S, Patten RD, Karas RH, Housman DE, Mendelsohn ME, Vasan RS, Benjamin EJ: Age-related changes in echocardiographic measurements: association with variation in the estrogen receptor-alpha gene. Hypertension 2007; 49(5):1000-1006. (PubMed ID Number: 17372038; Abstract)

Pou KM, Massaro JM, Hoffmann U, Vasan RS, Maurovich-Horvat P, Larson MG, Keaney JF, Jr., Meigs JB, Lipinska I, Kathiresan S, Murabito JM, O’Donnell CJ, Benjamin EJ, Fox CS: Visceral and subcutaneous adipose tissue volumes are cross-sectionally related to markers of inflammation and oxidative stress: the Framingham Heart Study. Circulation 2007; 116(11):1234-1241. (PubMed ID Number: 17709633; Abstract)

Quan SF, O’connor GT, Quan JS, Redline S, Resnick HE, Shahar E, Siscovick D, Sherrill DL: Association of physical activity with sleep-disordered breathing. Sleep Breath 2007; 11(3):149-157. (PubMed ID Number: 17221274; Abstract)

Romero JR: Prevention of ischemic stroke: overview of traditional risk factors. Curr Drug Targets 2007; 8(7):794-801. (PubMed ID Number: 17630932; Abstract)

Salaycik KJ, Kelly-Hayes M, Beiser A, Nguyen AH, Brady SM, Kase CS, Wolf PA: Depressive symptoms and risk of stroke: the Framingham Study. Stroke 2007; 38(1):16-21. (PubMed ID Number: 17138952; Abstract)

Samelson EJ, Cupples LA, Broe KE, Hannan MT, O’Donnell CJ, Kiel DP: Vascular calcification in middle age and long-term risk of hip fracture: the Framingham Study. J Bone Miner Res 2007; 22(9):1449-1454. (PubMed ID Number: 17542685; Abstract)

Seshadri S, DeStefano AL, Au R, Massaro JM, Beiser AS, Kelly-Hayes M, Kase CS, D’Agostino RB, Sr., Decarli C, Atwood LD, Wolf PA: Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham Study. BMC Med Genet 2007; 8 Suppl 1:S15. (PubMed ID Number: 17903297; Abstract)

Splansky GL, Corey D, Yang Q, Atwood LD, Cupples LA, Benjamin EJ, D’Agostino RB, Sr., Fox CS, Larson MG, Murabito JM, O’Donnell CJ, Vasan RS, Wolf PA, Levy D: The Third Generation Cohort of the National Heart, Lung, and Blood Institute’s Framingham Heart Study: design, recruitment, and initial examination. Am J Epidemiol 2007; 165(11):1328-1335. (PubMed ID Number: 17372189; Abstract)

Suter LG, Murabito JM, Felson DT, Fraenkel L: Smoking, alcohol consumption, and Raynaud’s phenomenon in middle age. Am J Med 2007; 120(3):264-271. (PubMed ID Number: 17349450; Abstract)

Tan ZS, Beiser AS, Vasan RS, Roubenoff R, Dinarello CA, Harris TB, Benjamin EJ, Au R, Kiel DP, Wolf PA, Seshadri S: Inflammatory markers and the risk of Alzheimer disease: the Framingham Study. Neurology 2007; 68(22):1902-1908. (PubMed ID Number: 17536046; Abstract)

Terry DF, Evans JC, Pencina MJ, Murabito JM, Vasan RS, Wolf PA, Kelly-Hayes M, Levy D, D’Agostino RB, Sr., Benjamin EJ: Characteristics of Framingham offspring participants with long-lived parents. Arch Intern Med 2007; 167(5):438-444. (PubMed ID Number: 17353490; Abstract)

Thakore AH, Guo CY, Larson MG, Corey D, Wang TJ, Vasan RS, D’Agostino RB, Sr., Lipinska I, Keaney JF, Jr., Benjamin EJ, O’Donnell CJ: Association of multiple inflammatory markers with carotid intimal medial thickness and stenosis (from the Framingham Heart Study). Am J Cardiol 2007; 99(11):1598-1602. (PubMed ID Number: 17531588; Abstract)

Troy LM, Jacques PF, Hannan MT, Kiel DP, Lichtenstein AH, Kennedy ET, Booth SL: Dihydrophylloquinone intake is associated with low bone mineral density in men and women. Am J Clin Nutr 2007; 86(2):504-508. (PubMed ID Number: 17684225; Abstract)

Vasan RS, Kannel WB: Are guidelines effectively guiding antihypertensive therapy? Am J Cardiol 2007; 100(1):143-144. (PubMed ID Number: 17599457; No Abstract)

Vasan RS, Larson MG, Aragam J, Wang TJ, Mitchell GF, Kathiresan S, Newton-Cheh C, Vita JA, Keyes MJ, O’Donnell CJ, Levy D, Benjamin EJ: Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study. BMC Med Genet 2007; 8 Suppl 1:S2. (PubMed ID Number: 17903301; Abstract)

Velagaleti RS, Vasan RS: Heart failure in the twenty-first century: is it a coronary artery disease or hypertension problem? Cardiol Clin. 2007 Nov;25(4):487-95; v. Review. (PubMed ID Number: 18063154; Abstract)

Wang TJ, Gona P, Larson MG, Levy D, Benjamin EJ, Tofler GH, Jacques PF, Meigs JB, Rifai N, Selhub J, Robins SJ, Newton-Cheh C, Vasan RS: Multiple biomarkers and the risk of incident hypertension. Hypertension 2007; 49(3):432-438 (PubMed ID Number: 17242302; Abstract)

Wang TJ, Larson MG, Benjamin EJ, Siwik DA, Safa R, Guo CY, Corey D, Sundstrom J, Sawyer DB, Colucci WS, Vasan RS: Clinical and echocardiographic correlates of plasma procollagen type III amino-terminal peptide levels in the community. Am Heart J 2007; 154(2):291-297 (PubMed ID Number: 17643579; Abstract)

Wang TJ, Larson MG, Keyes MJ, Levy D, Benjamin EJ, Vasan RS: Association of plasma natriuretic peptide levels with metabolic risk factors in ambulatory individuals. Circulation 2007; 115(11):1345-1353 (PubMed ID Number: 17339551; Abstract)

Widlansky ME, Vita JA, Keyes MJ, Larson MG, Hamburg NM, Levy D, Mitchell GF, Osypiuk EW, Vasan RS, Benjamin EJ: Relation of season and temperature to endothelium-dependent flow-mediated vasodilation in subjects without clinical evidence of cardiovascular disease (from the Framingham Heart Study). Am J Cardiol 2007; 100(3):518-523 (PubMed ID Number: 17659939; Abstract)

Weiner DE, Tighiouart H, Elsayed EF, Griffith JL, Salem DN, Levey AS, Sarnak MJ: The Framingham predictive instrument in chronic kidney disease. J Am Coll Cardiol. 2007 Jul 17;50(3):217-24. Epub 2007 Jul 2. (PubMed ID Number: 17631213; Abstract)

Wilk JB, Herbert A, Shoemaker CM, Gottlieb DJ, Karamohamed S: Secreted modular calcium-binding protein 2 haplotypes are associated with pulmonary function. Am J Respir Crit Care Med 2007; 175(6):554-560. (PubMed ID Number: 17204727; Abstract)

Wilk JB, Walter RE, Laramie JM, Gottlieb DJ, O’connor GT: Framingham Heart Study genome-wide association: results for pulmonary function measures. BMC Med Genet 2007; 8 Suppl 1:S8. (PubMed ID Number: 17903307; Abstract)

Wilson PW, Meigs JB, Sullivan L, Fox CS, Nathan DM, D’Agostino RB, Sr.: Prediction of incident diabetes mellitus in middle-aged adults: the Framingham Offspring Study. Arch Intern Med 2007; 167(10):1068-1074. (PubMed ID Number: 17533210; Abstract)

Wolf PA, Beiser A, Elias MF, Au R, Vasan RS, Seshadri S: Relation of obesity to cognitive function: importance of central obesity and synergistic influence of concomitant hypertension. The Framingham Heart Study. Curr Alzheimer Res 2007; 4(2):111-116. (PubMed ID Number: 17430232; Abstract)

Yang Q, Kathiresan S, Lin JP, Tofler GH, O’Donnell CJ: Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. BMC Med Genet 2007; 8 Suppl 1:S12. (PubMed ID Number: 17903294; Abstract)

Yang Q, Kim SK, Sun F, Cui J, Larson MG, Vasan RS, Levy D, Schwartz F: Maternal influence on blood pressure suggests involvement of mitochondrial DNA in the pathogenesis of hypertension: the Framingham Heart Study. J Hypertens 2007; 25(10):2067-2073. (PubMed ID Number: 17885549; Abstract)

Yoshida M, McKeown NM, Rogers G, Meigs JB, Saltzman E, D’Agostino R, Jacques PF: Surrogate markers of insulin resistance are associated with consumption of sugar-sweetened drinks and fruit juice in middle and older-aged adults. J Nutr 2007; 137(9):2121-2127. (PubMed ID Number: 17709452; Abstract)

Zhu H, Tucker HM, Grear KE, Simpson JF, Manning AK, Cupples LA, Estus S: A common polymorphism decreases low-density lipoprotein receptor exon 12 splicing efficiency and associates with increased cholesterol. Hum Mol Genet 2007; 16(14):1765-177. (PubMed ID Number: 17517690; Abstract)

Publications Since 2006:

Asztalos BF, Demissie S, Cupples LA, Collins D, Cox CE, Horvath KV, Bloomfield HE, Robins SJ, Schaefer EJ: LpA-I, LpA-I:A-II HDL and CHD-risk: The Framingham Offspring Study and the Veterans Affairs HDL Intervention Trial. Atherosclerosis 2006; 188(1):59-67 (PubMed ID Number: 16298372; Abstract)

Ellison RC, Zhang Y, Hopkins PN, Knox S, Djousse L, Carr JJ: Is alcohol consumption associated with calcified atherosclerotic plaque in the coronary arteries and aorta? Am Heart J 2006; 152(1):177-182 (PubMed ID Number: 16824853; Abstract)

Fox CS, Larson MG, Vasan RS, Guo CY, Parise H, Levy D, Leip EP, O’Donnell CJ, D’Agostino RB, Sr., Benjamin EJ: Cross-sectional association of kidney function with valvular and annular calcification: the Framingham Heart Study. J Am Soc Nephrol 2006; 17(2):521-527 (PubMed ID Number: 16382018; Abstract)

Herbert A, Gerry NP, McQueen MB, Heid IM, Pfeufer A, Illig T, Wichmann HE, Meitinger T, Hunter D, Hu FB, Colditz G, Hinney A, Hebebrand J, Koberwitz K, Zhu X, Cooper R, Ardlie K, Lyon H, Hirschhorn JN, Laird NM, Lenburg ME, Lange C, Christman MF: A common genetic variant is associated with adult and childhood obesity. Science 2006; 312(5771):279-283 (PubMed ID Number: 16614226; Abstract)

Wu LY, Sun L, Bull SB: Locus-specific heritability estimation via the bootstrap in linkage scans for quantitative trait loci. Hum Hered 2006; 62(2):84-96 (PubMed ID Number: 17047338; Abstract)

Yang Q, Guo CY, Cupples LA, Levy D, Wilson PW, Fox CS: Genome-wide search for genes affecting serum uric acid levels: the Framingham Heart Study. Metabolism 2005; 54(11):1435-1441 (PubMed ID Number: 16253630; Abstract)

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